Hi Friend,

People often ask me, “Have any of your therapies gone wrong?”



In starting Project Blueprint, I had one question: are we the first generation who won’t die?

To begin, my team and I evaluated all the scientific literature on longevity and aging, stack ranking the best performing health therapies with the most compelling evidence.

Caloric restriction was among the early selections. My daily calorie consumption dropped from 2,500 to 1,950. As a result, I got really lean and lost a lot of fat—especially in my face. My biomarkers were improving, but I looked gaunt. People thought I was on the brink of death.

As Blueprint grew into a global movement, the scrutiny increased. Facial fat, we discovered, is pretty important for how people perceive youth. It didn’t matter how good my biomarkers were if I didn’t have face fat.


Before Blueprint | Pre-Project Baby Face | After Project Baby Face

So, we started "Project Baby Face," to explore whether we can restore lost volume.

We selected a first therapy: injecting a fat-derived extracellular matrix to restore volume by stimulating my body’s natural fat growth. It’s possible to use one's own body fat for this but the problem was I didn’t have enough fat on my body to extract, so I used a donor.

Immediately following the injections, my face began to blow up. And then it got worse, and worse, and worse until I couldn’t even see. It was a severe allergic reaction.

Thirty minutes after the treatment, I was scheduled to meet with Ashlee Vance of Bloomberg to talk about Blueprint. I called him and said, “Hey, so that you’re not alarmed, you may not recognize me today. I think I’m ok. I hope I’m ok. If I’m not ok, are you by chance trained to perform any life-saving actions?”



Seven days later my face was back to normal and we were back in the trenches reformulating plans for our next attempt.

Building a product is one thing; being the product is a whole different thing. And I’ve never had more fun.

The full story of Project Baby Face:

Remember to go to bed on time.

Be well,

Bryan